Question: What Causes Your Antibodies To Be Low?

What are the symptoms of specific antibody deficiency?

People with selective antibody deficiency do not produce antibodies in response to polysaccharide vaccines.

Affected people have many sinus and lung infections and sometimes symptoms of allergies, such as a chronic runny and stuffy nose (rhinitis), a rash, and asthma..

What happens if you have low antibodies?

If your immune system makes low levels of antibodies, you may have a greater chance of developing repeated infections. You can be born with an immune system that makes low levels of antibodies, or your system may make low levels of antibodies in response to certain diseases, such as cancer.

How do you test for low immune system?

Since most of your immune ‘security guards’ live in your blood and bone marrow, a blood test is the primary way to check if your immune system is deficient. A Complete Blood Count (CBC) Lab Draw evaluates your numbers of white blood cells and antibodies to determine if your levels are cause for concern.

What is selective antibody deficiency?

Selective Antibody Deficiency (SAD), also known as specific antibody deficiency or partial antibody deficiency with impaired polysaccharide responsiveness, is a primary immune deficiency disease (PIDD) resulting from an individual’s inability to make antibodies to polysaccharide antigens found within encapsulated …

Can low IgG levels cause fatigue?

Isolated IgG1 deficiency has been reported in chronic fatigue syndrome. As IgG1 is the most abundant IgG subclass, its deficiency often results in hypogammaglobulinemia. Conversely, IgG2 and IgG4 deficiencies manifest in the form of otitis media and sinusitis.

What does it mean if your IgA is low?

Selective IgA deficiency is an immune system condition in which you lack or don’t have enough immunoglobulin A ( IgA ), a protein that fights infection (antibody). Most people with selective IgA deficiency don’t have recurrent infections.

What causes a weakened immune system?

Your immune system can also be weakened by smoking, alcohol, and poor nutrition. AIDS. HIV, which causes AIDS, is an acquired viral infection that destroys important white blood cells and weakens the immune system. People with HIV/AIDS become seriously ill with infections that most people can fight off.

Can IgA deficiency be improved?

There is no cure for IgA deficiency. Immunotherapy does not work to treat it. Complications for IgA deficiency include asthma, diarrhea, ear and eye infections, autoimmune diseases, and pneumonia.

What drugs can cause IgA deficiency?

Drugs such as phenytoin, sulfasalazine, gold, and D-penicillamine may lead to IgA deficiency in some patients.

Does low IgA mean celiac?

People with IgA deficiency should be tested for celiac disease because they are 10 to 20 times likely to develop an autoimmune response to gluten than the general population; Those with IgA deficiency should be tested for IgG-tTG antibodies instead of IgA-tTG .